[PDF] Molecular Biology of Human Cancers An Advanced Student’s Textbook – Wolfgang A. Schulz
Free Download:
Available
Molecular Biology of Human Cancers An Advanced Student’s Textbook – Wolfgang A. Schulz
About this Textbook
Over the last three decades, knowledge on the molecular biology of human cancers has vastly expanded. A host of genes and proteins involved in cancer development and progression have been defined and many mechanisms at the molecular, cellular and even tissue level have been, at least partly, elucidated. Insights have also been gained into the molecular mechanisms underlying carcinogenesis by chemical, physical, and biological agents and into inherited susceptibility to cancer.
Accordingly, Part I of the book presents many of the molecules and mechanisms generally important in human cancers. Following an overview on the cancer problem, individual chapters deal with cancer genetics and epigenetics, DNA damage and repair, oncogenes, tumor suppressors, regulatory pathways in cancer, apoptosis, cellular senescence, tumor invasion, and metastasis.
A consensus is emerging that while these common mechanisms and molecules are all relevant to human cancers, in each cancer type (or even subtype) a selection of them are extremely important. For selected cancers, the route from genetic and epigenetic changes to their biological and clinical behavior can already be traced. Part II of the book presents a broad, but exemplary selection of cancers that serve as paradigms to illustrate this point.
In fact, cancer research has now reached a critical stage, in which the accumulated knowledge on molecular mechanisms is gradually translated into improved prevention, diagnosis, and treatment. The state, pitfalls, and potential of these efforts are summarized in Part III.
More than ever, cancer research is now an interdisciplinary effort which requires a basic knowledge of commonly used terms, facts, issues, and concepts. The aim of this book is to provide advanced students and practitioners of different disciplines with this basis, bridging the gap between standard textbooks of molecular biology, pathology, and oncology on the one hand and the specialized cancer literature on the other.
[PDF] Molecular Biology of Human Cancers An Advanced Student’s Textbook – Wolfgang A. Schulz Book Details
Molecular Biology of Human Cancers : An Advanced Student’s Textbook
We use technologies like cookies to store and/or access device information. We do this to improve browsing experience and to show (non-) personalized ads. Consenting to these technologies will allow us to process data such as browsing behavior or unique IDs on this site. Not consenting or withdrawing consent, may adversely affect certain features and functions.
Functional
Always active
The technical storage or access is strictly necessary for the legitimate purpose of enabling the use of a specific service explicitly requested by the subscriber or user, or for the sole purpose of carrying out the transmission of a communication over an electronic communications network.
Preferences
The technical storage or access is necessary for the legitimate purpose of storing preferences that are not requested by the subscriber or user.
Statistics
The technical storage or access that is used exclusively for statistical purposes.The technical storage or access that is used exclusively for anonymous statistical purposes. Without a subpoena, voluntary compliance on the part of your Internet Service Provider, or additional records from a third party, information stored or retrieved for this purpose alone cannot usually be used to identify you.
Marketing
The technical storage or access is required to create user profiles to send advertising, or to track the user on a website or across several websites for similar marketing purposes.